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Bacterial Infections in Childhood: Pertussis

Description

Pertussis Toxins : Any of various biologically active proteins or toxins elaborated by Bordetella pertussis that cause the symptoms of whooping cough. Some activate pancreatic islets, others inhibit the adenylate cyclase cascade and some cause lymphocytosis. [1]

Whooping Cough : A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath. [1]

Bordetella pertussis : A species of gram-negative, aerobic bacteria that is the causative agent of WHOOPING COUGH. Its cells are minute coccobacilli that are surrounded by a slime sheath. [1]

Diphtheria-Tetanus-Pertussis Vaccine : A vaccine consisting of DIPHTHERIA TOXOID, TETANUS TOXOID, and whole-cell PERTUSSIS VACCINE. The vaccine protects against diphtheria, tetanus, and whooping cough. [1]

Erythromycin A bacteriostatic antibiotic substance produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. [1]

[1] MeSH 2001 © National Library of Medicine


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Pertussis
Whooping cough
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Whooping Cough
Bordetella pertussis
Pertussis Toxins
Erythromycin

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Whooping Cough
Bordetella pertussis
Pertussis Toxins
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  http://www.hon.ch/Dossier/MotherChild/child_bacteria/bacteria_pertussis.html Last modified: Jun 24 2002