Bacterial Infections in Childhood: Pertussis
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Description
Pertussis Toxins : Any of various biologically active proteins or toxins
elaborated by Bordetella pertussis that cause the symptoms of whooping
cough. Some activate pancreatic islets, others inhibit the adenylate cyclase
cascade and some cause lymphocytosis. [1]
Whooping Cough :
A respiratory infection caused by BORDETELLA
PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged
crowing intake of breath.
[1]
Bordetella pertussis :
A species of gram-negative, aerobic bacteria that is the
causative agent of WHOOPING COUGH. Its cells are minute coccobacilli that
are surrounded by a slime sheath.
[1]
Diphtheria-Tetanus-Pertussis Vaccine :
A vaccine consisting of DIPHTHERIA TOXOID, TETANUS
TOXOID, and whole-cell PERTUSSIS VACCINE. The vaccine protects
against diphtheria, tetanus, and whooping cough.
[1]
Erythromycin
A bacteriostatic antibiotic substance produced by
Streptomyces erythreus. Erythromycin A is considered its major active
component. In sensitive organisms, it inhibits protein synthesis by binding to
50S ribosomal subunits. This binding process inhibits peptidyl transferase
activity and interferes with translocation of amino acids during translation and
assembly of proteins.
[1]
[1]
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Introduction
