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Viral Infections in Childhood: Polio
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Description
Polio or poliomyelitis
is an infectious viral disease of the central nervous system. The greatest
incidence of the disease, also known as infantile paralysis, is in children
between the ages of 5 and 10 years.
Because of the widespread use of polio vaccines, wild poliovirus (i.e.
not due to the vaccine) has not been found in the Western Hemisphere since
1991. The World Health Organization has set the goal of eliminating poliovirus
world-wide by the year 2000. The disease is most prevalent in areas of
Africa, the Middle East, and South Asia.
Symptoms and Signs
Most infections are subclinical, having no symptoms, or
abortive (not completely developed), which causes slight fever, malaise,
headache, sore throat, and vomiting.
Major polio involves the central nervous system and takes
two forms:
- Nonparalytic , with moderate fever,
headache, vomiting, lethargy, irritability, and pain in the neck,
back, arms, legs, and abdomen; and
- Paralytic , with the same symptoms as
nonparalytic plus asymmetrical muscle weakness, loss of reflexes,
urine retention, constipation, a tingling or burning sensation on
the skin, and paralysis.
Diagnosis and Treatment
Arm or leg paralysis but no numbness; analysis of cerebrospinal
fluid for protein level through lumbar puncture. Diagnosis is confirmed
by identifying poliovirus in a stool sample and detecting high levels
of antibodies to the virus in the blood.
Treatment is for the problems polio may cause, rather than for the polio
itself.
Two types of vaccine are available: an inactivated poliovirus vaccine
( Salk vaccine ) given by injection and a live
poliovirus vaccine ( Sabin vaccine ) taken
orally. The live oral vaccine provides better immunity and is usually
preferred but can, in very rare cases, cause polio in people with a weakened
immune system and so is not given to these people or those who will be
around such people.
Postpoliomyelitis
Syndrome
An estimated 20 to 40% of patients who initially recover
from poliomyelitis later develop post-polio syndrome (PPS). Appearing
an average of 30 to 40 years after the initial illness, PPS causes fatigue,
muscle weakness, and muscle and joint pain. These symptoms often worsen
after exercise. Some patients also have trouble breathing or swallowing
and suffer from muscle twitches and other symptoms. Although PPS is not
life threatening, it can severely limit a patient's lifestyle and mobility,
making it difficult for the patient to continue a job or carry out daily
activities. Scientists do not know what causes PPS, and there is no cure.
Rest, over-the-counter or prescription pain relievers, physical therapy,
and devices such as canes and wheelchairs help patients control their
symptoms.
The information in this page is presented in summarised form and has been taken
from the following source(s):
1.
Intelihealth.com, Children's Health Section: http://www.intelihealth.com/
2.
Microsoft® Encarta® Online Encyclopaedia, ©1997-2000 Microsoft Corporation.
All rights reserved. 2000: http://encarta.msn.com
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