An essential, unsaturated, 20 carbon fatty acid that humans use to synthesize regulatory molecules such as
prostaglandins and thromboxanes.
As the is activated, several other events occur that contribute to the
pathophysiology of allergic diseases. One such event is the activation of a membrane
enzyme called , which breaks down membrane components to
arachidonic acid . Arachidonic acid is further metabolized by one of two enzyme pathways into various
(by cyclooxygenase) or (by lipooxygenase). Both prostaglandins and leucotrienes are highly