Antibody Dependant Cell Mediated Cytotoxicity (ADCC)
Type VI Hypersensitivity
Type VI reaction according to the
Gell and Coombs Classification . A phenomenon in which target cells, coated with antibody, are destroyed by
specialized killer cells
( NK cells , Killer T-cells and macrophages ), which bear receptors for the Fc portion of the coating antibody (Fc receptors).
These receptors allow the killer cells to bind to the anti-body-coated target.
Eosinophils kill helminths (parasitic larvae infections) by ADCC.