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Viral Infections in Childhood: Infectious Mononucleosis


Infectious Mononucleosis : A common, acute infection usually caused by the Epstein-Barr virus (HERPESVIRUS 4, HUMAN). There is an increase in mononuclear white blood cells and other atypical lymphocytes, generalized lymphadenopathy, splenomegaly, and occasionally hepatomegaly with hepatitis. [1]

Herpesvirus 4, Human : A species of LYMPHOCRYPTOVIRUS cultivated from cultures of BURKITT LYMPHOMA. It is thought to be the causative agent of INFECTIOUS MONONUCLEOSIS. [1]

Epstein-Barr Virus Infections : Infection with human herpesvirus 4 (HERPESVIRUS 4, HUMAN) which may facilitate the development of various lymphoproliferative disorders. These include BURKITT LYMPHOMA (African type), INFECTIOUS MONONUCLEOSIS, and oral hairy leukoplakia (LEUKOPLAKIA, HAIRY). [1]

Cytomegalovirus : A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS. [1]

Adenoviridae : A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases. [1]

Leukocytes, Mononuclear : Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules. [1]

[1] MeSH 2001 © National Library of Medicine

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Infectious mononucleosis


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